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Clara Campàs Selected Research

acadesine

8/2015Bcl-2high mantle cell lymphoma cells are sensitized to acadesine with ABT-199.
2/2014Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma.
3/2013Acadesine for patients with relapsed/refractory chronic lymphocytic leukemia (CLL): a multicenter phase I/II study.
10/2010AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells.
5/2003Acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes.

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Clara Campàs Research Topics

Disease

8B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
02/2014 - 04/2002
4Neoplasms (Cancer)
08/2015 - 12/2006
3Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
08/2015 - 12/2006
2Lymphoma (Lymphomas)
02/2014 - 12/2006
2Ataxia Telangiectasia (Louis Bar Syndrome)
10/2010 - 05/2006
1Hyperuricemia
03/2013

Drug/Important Bio-Agent (IBA)

5acadesineIBA
08/2015 - 05/2003
2NucleosidesIBA
08/2015 - 02/2014
2AICA ribonucleotide (ZMP)IBA
02/2014 - 10/2010
2Proteins (Proteins, Gene)FDA Link
10/2010 - 12/2006
1Pharmaceutical PreparationsIBA
08/2015
1venetoclaxIBA
08/2015
1MetalsIBA
02/2014
1Monoclonal AntibodiesIBA
02/2014
1Rituximab (Mabthera)FDA Link
02/2014
1Allopurinol (Remid)FDA LinkGeneric
03/2013
1Antineoplastic Agents (Antineoplastics)IBA
12/2007
1PK 11195 (PK11195)IBA
12/2007
1Protein Kinase C betaIBA
12/2006
1Antimycin AIBA
12/2006
1Phosphatidylinositols (Phosphatidylinositol)IBA
12/2006
1nutlin 3IBA
05/2006
1Protein Kinases (Protein Kinase)IBA
11/2003
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
04/2002
1Protein Kinase CIBA
04/2002

Therapy/Procedure

1Therapeutics
02/2014
1Drug Therapy (Chemotherapy)
12/2006